BAICALEIN VS BAICALIN
Baicalin and baicalein both exhibited modest anti-inflammatory characteristics, however baicalein emerged as the more potent substance due to its stronger inhibitory activity on Src tyrosine kinase and cytokine IL-6 production.
BAICALIN
WHAT IS THE BENEFIT OF BAICALIN?
According to multiple studies, baicalin successfully inhibits a variety of neurodegenerative illnesses, including AD, PD, and cerebral ischemia. By lowering oxidative stress, preventing excitotoxicity, encouraging neurogenesis, lowering apoptosis, and preventing the generation of inflammatory cytokines, it does this.
WHERE DOES BAICALEIN ORIGINALLY COME?
A flavone glycoside known as baicalin hydrolyzes to form an aglycone (baicalein). It is found in abundance in the leaves and stem bark of Scutellaria plants (Lamiaceae) and is widely dispersed in the fruit, roots, and leaves as a main component.
EFFECTS OF BAICALIN HAVE
According to research, baicalin (50, 100, and 200 mg/kg BW) inhibited the NF-B pathway in chicken liver after LPS-induced infection by blocking the TLR4 receptor. The primary mode of action is the inhibition of the expression of inflammatory markers like iNOS, IL-1, COX-2, TNF-, and IL-6.
TREATS GLAUCOMA
The degenerative alterations in the retinal tissues of glaucoma animals were reduce as a result of baicalin activating PI3K/AKT signalling to prevent autophagy. According to these results, baicalin is a potential medication for the treatment of glaucoma.
BALICINE FOR SKIN
An effective UV-ray absorber with anti-inflammatory and antioxidant characteristics, baicalin is derived from plants and may help slow the effects of photoaging.
BAICALEIN
It functions as an antioxidant, a prostaglandin, and a hormone antagonist.
WHAT IS THE PURPOSE OF BAICALEIN?
Flavones such as baicalin and baicalein , which have anti-inflammatory and anticancer activities, have a variety of biological effects. In a range of human cancer cell lines, both natural compounds limit cancer cell proliferation and trigger apoptosis.
WHAT FOODS HAVE A HIGH BAICALEIN CONTENT?
The bioflavonoids, which include quercetin, baicalein, apigenin, luteolin, and myricetin, are the most common polyphenolic compounds in nature. They are present in all plant life, as well as in wine, tea, citrus fruits, dark chocolate, and herbs.
ARE BAICALEIN AND SKULLCAP THE SAME?
S. baicalensis is a root extract use in traditional medicine. It is often refer to as Huang Qin or Chinese skullcap. It frequently functions best when combined with other plants. Most investigations, which have suggested anti-inflammatory and antioxidant efficacy, have been conduct in laboratories rather than on humans.
METABOLIZE DRUGS IN BODY
Baicalein inhibits the cytochrome P450 system enzyme CYP2C9,[16] which is responsible for the body’s drug metabolization.
WHAT MAKES BAICALIN AND BAICALEIN DIFFERENT FROM ONE ANOTHER?
Both in vivo and in vitro, baicalein is more effective than baicalin at inhibiting angiogenesis. Together, the study’s results indicate that baicalein and baicalin have the capacity to inhibit angiogenesis, a hitherto undiscovered physiological action.
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